LIP1 (human) trifluoroacetate saltCatalog Number332P912Three Letter CodeH-Ala-Arg-Ser-Ala-Pro-Ala-Ala-Ala-Ile-Ala-Ala-Arg-Val-Ala-Gly-Gln-Thr-Arg-Asn-Ile-Thr-Val-Asp-Pro-Arg-Leu-Phe-Lys-Lys-OH trifluoroacetate saltOne Letter CodeARSAPAAAIAARVAGQTRNITVDPRLFKKSynonymsPrepro-β-Nerve Growth Factor (51-79) (human), Prepro-β-NGF (51-79) (human)Molecular FormulaC???H???N??O??Relative Molecular Mass3050.56CAS Registry NumberSourceSyntheticStorage Conditions-20 ± 5 °CAreas of InterestCancer Research|Growth FactorsDetailsLIP1 is a peptide derived from the proregion of the nerve growth factor (NGF). The 29 amino acid peptide shows multiple biological activities. It induces F-actin rearrangement, phosphorylation of TrkA and Akt, exerts anti-proliferative effects on the mitogenic activity of estrogen and IGF in MCF-7 breast cancer cells, and is neuroprotective in vivo and in vitro. Similar to LIP2 (H-6602) high levels of LIP1 are present in the sera and the synovial fluid of rheumatoid arthritis patients.